ADME PROPERTIES PREDICTION OF 5-PHENYL-5,6-DIHYDROTETRAZOLO[1,5-c] QUINAZOLINES

نویسندگان

چکیده

Due to the recent predicted affinity of 13 novel 5-phenyl-5,6-dihydrotetrazolo[1,5-c]-quinazolines ribosomal 50S protein L2P (2QEX) by molecular docking, their ADME properties were calculated at site SwissADME predict drug-likeness. Hence, substances 6, 10, and 12 appeared be leading compounds among all studied ones are definite interest for further in vitro antimicrobial activity investigation.

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ژورنال

عنوان ژورنال: Grail of science

سال: 2022

ISSN: ['2710-3056']

DOI: https://doi.org/10.36074/grail-of-science.29.04.2022.124